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Acquisition of ESBL-PE by newborns in a low-income country - NeoLIC
Inclusion criteria: 1. For the epidemiological study: All members of 60 households in which a newborn was just born Inclusion criteria for the mother at the time of birth, pregnant woman: _ have a monofetal pregnancy - regularly live in the study area OR plan to live in the study area live during the study period; - have been informed about research and the taking of biological samples from yourself and your newborn; - have given their consent to the conduct of the research and the associated collection of biological samples and - have signed the declaration of consent (or its witnesses, if applicable). Inclusion criteria for the living newborn at birth, newborns: - life after birth; - whose parents or legal representatives are present: - stay regularly in the study area or plan to stay in the study area during the study duration; - were informed about the research and the related collection of biological samples on your newborn; - have given their consent to conduct the research and the associated collection of biological samples, inclusion criteria for the household member, residing: - from the same household as the mother-child couple - stay at least 4 nights per week in this house - after having given his consent to carry out the research and the associated collection of biological samples, - and have signed the consent of the study (or its witness or its legal), if applicable, representative) 2. For the anthropological study with interviews: 16 houses are selected from To the 60 Houses included: 8 houses in which the child did not acquire an ESBL-E during the entire follow-up and 8 houses in which the child acquired at least an ESBL-E once during the follow-up. Interviews are carried out among these households with: 16 mothers or responsible for the child only in the absence of the mother 4 people with a mother role for the child (grandmother, aunts ... Interviews selected: 2 households in which the child did not acquire ESBL-E during all follow-up examinations and 2 households in which the child acquired at least one BLSE-E during their follow-up examination Inclusion criteria for direct participation observations - residents of the same household as that Mother-child couple - have agreed to take part in the study - after giving their consent to conduct the research, - and have signed the consent of the study (or their witness or their legal), if applicable, representative) Exclusion criteria: For the epidemiological part: - Pregnant women: non-monofetal pregnancy rschaft - Newborn: died during childbirth - House residents: None 2. and 3) For the anthropological part: • Semi-structured interview: For household members: - do not react to the structural family and social functions of the child Environment For health workers and district managers - People who do not fulfill the intended functions - do not practice in the residential area • Direct observation of the participants: - do not live in the same household as the mother-child couple.
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